Fig. 1

Delayed development of temporal processing in the frontal cortex of female Fmr1 KO mice. Individual example heatmaps of ITPC generated at 40 Hz at multiple gap durations in p21, p30, and p60 WT (A: AC, C: FC) and Fmr1 KO (B: AC, D: FC) female mice. Qualitative observations of these examples show deficits in cortical temporal processing at p21, but not p30 or p60, in the FC KO mice. No deficits are seen in the AC at any age. All panels show 100% modulation depth. The onset of the gap-ASSR stimulus is at 0 ms in each panel