Table 3 Analysis of power spectral dynamics during baseline light and dark phase recordings using two-way ANOVA with genotype (group 1: matDp/ + , WT; group 2: patDp/ + , WT; group 3: Ube3a, WT) and time (2-h bins) as factors, and average beta power across time using t test. Interactions reported for genotype x time
From: Sleep EEG signatures in mouse models of 15q11.2-13.1 duplication (Dup15q) syndrome
Frequency | State | Genotype | Interactions | |||
|---|---|---|---|---|---|---|
Light phase | Dark phase | |||||
Beta | Wake | matDp/ +  | F (5, 75) = 0.5442 | P = 0.7422 | F (5, 75) = 0.4737 | P = 0.7947 |
patDp/ +  | F (5, 30) = 0.5573 | P = 0.7316 | F (5, 30) = 0.6159 | P = 0.6886 | ||
Ube3a | F (5, 30) = 2.115 | P = 0.0910 | F (5, 30) = 0.2150 | P = 0.9534 | ||
NREM | matDp/ +  | F (5, 75) = 0.4544 | P = 0.8088 | F (5, 75) = 1.250 | P = 0.2945 | |
patDp/ +  | F (5, 30) = 1.073 | P = 0.3948 | F (5, 30) = 0.6643 | P = 0.6533 | ||
Ube3a | F (5, 30) = 1.383 | P = 0.2587 | F (5, 30) = 0.5622 | P = 0.7281 | ||
REM | matDp/ +  | F (5, 75) = 0.6822 | P = 0.6384 | F (5, 75) = 0.4315 | P = 0.8253 | |
patDp/ +  | F (5, 30) = 0.3498 | P = 0.8783 | F (5, 30) = 1.346 | P = 0.2723 | ||
Ube3a | F (5, 30) = 1.288 | P = 0.2951 | F (5, 30) = 1.345 | P = 0.2729 | ||
Beta_average | Wake | matDp/ +  | t = 2.145, df = 15 | P = 0.0487 | t = 2.168, df = 15 | P = 0.0467 |
NREM | matDp/ +  | t = 3.536, df = 15 | P = 0.0030 | t = 3.337, df = 15 | P = 0.0045 | |
REM | matDp/ +  | t = 2.882, df = 15 | P = 0.0114 | t = 2.724, df = 15 | P = 0.0157 | |
Delta | Wake | matDp/ +  | F (5, 75) = 1.151 | P = 0.3414 | F (5, 75) = 1.502 | P = 0.1994 |
patDp/ +  | F (5, 30) = 0.5903 | P = 0.7073 | F (5, 30) = 0.7578 | P = 0.5872 | ||
Ube3a | F (5, 30) = 1.734 | P = 0.1572 | F (5, 30) = 0.5635 | P = 0.7271 | ||
NREM | matDp/ +  | F (5, 75) = 0.2177 | P = 0.9539 | F (5, 75) = 1.117 | P = 0.3585 | |
patDp/ +  | F (5, 30) = 0.9128 | P = 0.4860 | F (5, 30) = 0.5793 | P = 0.7154 | ||
Ube3a | F (5, 30) = 1.160 | P = 0.3517 | F (5, 30) = 0.7352 | P = 0.6029 | ||
Theta | REM | matDp/ +  | F (5, 75) = 0.8366 | P = 0.5279 | F (5, 75) = 0.3561 | P = 0.8768 |
patDp/ +  | F (5, 30) = 0.5433 | P = 0.7419 | F (5, 30) = 0.1093 | P = 0.9894 | ||
Ube3a | F (5, 30) = 2.223 | P = 0.0779 | F (5, 30) = 1.619 | P = 0.1854 | ||