Table 5 Analysis of power spectral dynamics in light and dark phase recordings during recovery after 6 h of sleep deprivation, using two-way ANOVA with genotype (group 1: matDp/ + , WT; group 2: patDp/ + , WT; group 3: Ube3a, WT) and time (2-h bins) as factors, and average beta power across time using t test. Interactions reported for genotype x time
From: Sleep EEG signatures in mouse models of 15q11.2-13.1 duplication (Dup15q) syndrome
Frequency | State | Genotype | Interactions | |||
|---|---|---|---|---|---|---|
Light phase | Dark phase | |||||
Beta | Wake | matDp/ +  | F (5, 75) = 0.8756 | P = 0.5017 | F (5, 75) = 0.7173 | P = 0.6124 |
patDp/ +  | F (5, 30) = 0.09704 | P = 0.9919 | F (5, 30) = 1.581 | P = 0.1957 | ||
Ube3a | F (5, 30) = 0.6072 | P = 0.6949 | F (5, 30) = 0.4081 | P = 0.8393 | ||
NREM | matDp/ +  | F (3, 45) = 11.42 | P < 0.0001 | F (5, 75) = 3.256 | P = 0.0103 | |
patDp/ +  | F (3, 18) = 2.404 | P = 0.1011 | F (5, 30) = 2.402 | P = 0.0603 | ||
Ube3a | F (3, 18) = 0.7913 | P = 0.5145 | F (5, 30) = 1.526 | P = 0.2114 | ||
REM | matDp/ +  | F (3, 45) = 0.8003 | P = 0.5003 | F (5, 75) = 0.8321 | P = 0.5310 | |
patDp/ +  | F (3, 18) = 1.231 | P = 0.3276 | F (5, 30) = 0.8958 | P = 0.4965 | ||
Ube3a | F (3, 18) = 0.4818 | P = 0.6991 | F (5, 30) = 1.838 | P = 0.1355 | ||
Beta_average | Wake | matDp/ +  | t = 2.464, df = 13 | P = 0.0284 | t = 1.649, df = 14 | P = 0.1215 |
NREM | matDp/ +  | t = 2.183, df = 13 | P = 0.048 | t = 2.215, df = 13, | P = 0.0452 | |
REM | matDp/ +  | t = 1.290, df = 14 | P = 0.2179 | t = 1.082, df = 14 | P = 0.2976 | |
Delta | Wake | matDp/ +  | F (5, 75) = 1.099 | P = 0.3684 | F (5, 75) = 0.2749 | P = 0.9255 |
patDp/ +  | F (5, 30) = 0.04741 | P = 0.9985 | F (5, 30) = 1.660 | P = 0.1749 | ||
Ube3a | F (5, 30) = 2.283 | P = 0.0715 | F (5, 30) = 1.725 | P = 0.1592 | ||
NREM | matDp/ +  | F (3, 45) = 2.574 | P = 0.2111 | F (5, 75) = 1.583 | P = 0.1753 | |
patDp/ +  | F (3, 18) = 0.7020 | P = 0.5631 | F (5, 30) = 2.298 | P = 0.0700 | ||
Ube3a | F (3, 18) = 0.9471 | P = 0.4387 | F (5, 30) = 1.657 | P = 0.1756 | ||
Theta | REM | matDp/ +  | F (3, 39) = 2.368 | P = 0.0855 | F (5, 65) = 1.091 | P = 0.3741 |
patDp/ +  | F (3, 18) = 1.149 | P = 0.3563 | F (5, 30) = 0.7484 | P = 0.5937 | ||
Ube3a | F (3, 15) = 0.8304 | P = 0.4977 | F (5, 25) = 0.2709 | P = 0.9247 | ||