Fig. 5
From: Altered individual-level morphological similarity network in children with growth hormone deficiency
Relationship between the nodal properties and clinical variables in GHD group. In pediatric GHD, serum IGF-1 concentration was positively correlated with Eglob (r = 0.354; P = 0.006, A), and negatively correlated with Lp (r = -0.329; P = 0.011, B), λ (r = -0.306; P = 0.018, C). As for nodal profiles, serum IGF-1 concentration was positively correlated with nodal efficiency of the right ACG (r = 0.264; P= 0.043, D), and negatively correlated with nodal degree of the left cerebellum 4-5 (r = -0.356; P = 0.006, E), nodal efficiency of the left cerebellum 4-5 (r = -0.350; P = 0.007, F). Then, serum GH peak level was negatively correlated with nodal degree of the left cerebellum 4-5 (r = -0.309; P = 0.016, G) and nodal efficiency of the left cerebellum 4-5 (r = -0.294; P = 0.023, H). Total scores of Achenbach's CBCL were positively correlated with nodal degree of the left amygdala (r = 0.284; P = 0.037, I), nodal efficiency of the left amygdala (r = 0.273; P = 0.046, J), nodal degree of the vermis 3 (r = 0.300; P = 0.028, K), and nodal efficiency of the vermis 3 (r = 0.276; P = 0.044, L). Abbreviations: GHD = growth hormone deficiency; IGF-1 = insulin-like growth factor-1; ACG = anterior cingulate and paracingulate gyri