Fig. 3

The correlation metric (Full-eur1kg ASD-PGS versus Target-eur1kg ASD-PGS) representing loss of information in each of the four target cohorts. Legend: The metric represents information loss or genome-wide coverage from using a pruning and thresholding derivation method in each of the four target cohorts. Thresholds for discovery p-values are genome-wide significant (5 × 10–8), genome-wide suggestion (1 × 10–6), 0.05 and 0.20