UFA type | Mutation type | Â | N (%) | Adjusted odds ratio (aOR) a | 95% CI | |
---|---|---|---|---|---|---|
Any UFA (N = 43) | Cluster 1 | No | 42(36.5) | Ref. |  | |
Yes | 1(9.1) | 0.16 | 0.02–1.32 | |||
Cluster 2 | No | 37(33.0) | Ref. | Â | ||
Yes | 6(42.9) | 1.64 | 0.52–5.14 | |||
Cluster 3 | No | 34(30.9) | Ref. | Â | ||
Yes | 9(56.3) | 2.87 | 0.98–8.44 | |||
Cluster 4 | No | 29(29.3) | Ref. | Â | ||
Yes | 14(51.9) | 2.76 | 1.14–6.68 | |||
Structural anomalies (N = 20) | Cluster 1 | No | 119(16.5) | Ref. |  | |
Yes | 1(9.1) | 0.50 | 0.06–4.14 | |||
Cluster 2 | No | 16(14.3) | Ref. | Â | ||
Yes | 4(28.6) | 2.46 | 0.68–8.86 | |||
Cluster 3 | No | 16(14.5) | Ref. | Â | ||
Yes | 4(25.0) | 1.95 | 0.56–6.81 | |||
Cluster 4 | No | 11(11.1) | Ref. | Â | ||
Yes | 9(33.3) | 4.07 | 1.47–11.30 | |||
Soft markers (N = 26) | Cluster 1 | No | 25(21.7) | Ref. |  | |
Yes | 1(9.1) | 0.32 | 0.04–2.73 | |||
Cluster 2 | No | 23(20.5) | Ref. | Â | ||
Yes | 3(21.4) | 1.18 | 0.30–4.43 | |||
Cluster 3 | No | 20(18.2) | Ref. | Â | ||
Yes | 6(37.5) | 2.73 | 0.86–8.62 | |||
Cluster 4 | No | 21(21.2) | Ref. | Â | ||
Yes | 5(18.5) | 0.89 | 0.30–2.68 | |||
Head and brain (N = 12) | Cluster 1 | No | 12(10.4) | Ref. |  | |
Yes | 0(0.0) | NA | NA | |||
Cluster 2 | No | 10(8.9) | Ref. | Â | ||
Yes | 2(14.3) | 1.73 | 0.34–8.92 | |||
Cluster 3 | No | 9(8.2) | Ref. | Â | ||
Yes | 3(18.8) | 2.58 | 0.62–10.77 | |||
Cluster 4 | No | 6(6.1) | Ref. | Â | ||
Yes | 6(22.2) | 4.50 | 1.31–15.42 | |||
Urinary system (N = 14) | Cluster 1 | No | 14(12.2) | Ref. |  | |
Yes | 0(0.0) | NA | NA | |||
Cluster 2 | No | 12(10.7) | Ref. | Â | ||
Yes | 2(14.3) | 1.52 | 0.30–7.76 | |||
Cluster 3 | No | 10(9.1) | Ref. | Â | ||
Yes | 4(25.0) | 3.31 | 0.89–12.38 | |||
Cluster 4 | No | 9(9.1) | Ref. | Â | ||
Yes | 5(18.5) | 2.41 | 0.72–8.06 | |||
Heart (N = 18) | Cluster 1 | No | 17(14.8) | Ref. |  | |
Yes | 1(9.1) | 0.55 | 0.07–4.63 | |||
Cluster 2 | No | 16(14.3) | Ref. | Â | ||
Yes | 2(14.3) | 1.07 | 0.22–5.31 | |||
Cluster 3 | No | 16(14.5) | Ref. | Â | ||
Yes | 2(12.5) | 0.82 | 0.17–3.98 | |||
Cluster 4 | No | 14(14.1) | Ref. | Â | ||
Yes | 4(14.8) | 1.10 | 0.33–3.68 |