Table 1 Cohort demographics
Cohort | 22qDS | Cardiac | Control |
|---|---|---|---|
N (Male: Female) | 7 (4:3) | 14 (10:4) | 12 (8:4) |
Gestational age at scan, weeks (median [IQR]) | 31.71 [31.57-33.00] | 31.71 [31.17–31.86] | 31.71 [31.11–32.15] |
Primary cardiac defect, N | Isolated right aortic arch: 2 Common arterial trunk: 2 Interrupted aortic arch: 2 Pulmonary atresia + VSD: 1 | Isolated right aortic arch: 8 Common arterial trunk: 4 Interrupted aortic arch: 2 Pulmonary atresia + VSD: 2 | - |
Structural brain abnormalities, N | Prominent cavum septum pellucidum: 1 | - | - |
Extracardiac abnormalities, N | Absent or hypoplastic thymus: 3 | - | - |