The striatal matrix compartment is expanded in autism spectrum disorder

Table 1 Normalized matrix-like volume (± standard error of the mean) is expanded in autism spectrum disorder (ASD) relative to matched typically developing (TD) controls in somatotopic zones specific for each of the ten bait regions utilized for striatal parcellation. * indicates a significant increase in matrix-like volume

Somatopic Zone	Mean, Normalized Matrix Volume ± SEM	p-value, ASD vs. TD
Primary Sensory	115 ± 11%	0.21
VLc-VPLo Thal	106 ± 10%	0.35
Supplementary Motor	124 ± 6.9%	0.010*
Primary Motor	142 ± 7.8%	0.014*
Globus Pallidus Int	147 ± 11%	0.0062*
Mediodorsal Thal	110 ± 5.2%	0.11
Post. Orbitofrontal	115 ± 4.9%	0.0064*
Anterior Insula	123 ± 4.3%	0.010*
Basolateral Amyg	126 ± 8.8%	0.033*
Basal Operculum	120 ± 5.4%	0.0095*

ISSN: 1866-1955