Protein-truncating variants and deletions of SHANK2 are associated with autism spectrum disorder and other neurodevelopmental concerns

Table 5 Developmental Profile-4 results

Domain	Mean (SD)	Qualitative Descriptor	Participants Below 70 (percentage)
Physical	78.2 (20)	Below Average	44%
Adaptive Behavior	68.7 (12.1)	Delayed	56%
Social-Emotional Skills	68.9 (7.8)	Delayed	44%
Cognitive	65.4 (11.3)	Delayed	44%
Communication	68.7 (8.7)	Delayed	44%

Legend: DP-4 results by mean, standard deviation, and qualitative descriptor of the mean. Percentage of the 9 participants below a score of 70 represent those two standard deviations below the normative mean, indicating significant delays

ISSN: 1866-1955