Protein-truncating variants and deletions of SHANK2 are associated with autism spectrum disorder and other neurodevelopmental concerns

Table 7 SHANK2/PMS adaptive behavior comparison

Domain	SHANK2 (n = 10)	PMS (n = 63)	t-test p value
Domain	Mean (SD)		t-test p value
Composite	59.1 (15.34)	44.1 (17.6)	0.017*
Communication	47.8 (12.7)	35.1 (17.6)	0.019*
Daily Living Skills	65.0 (18.37)	46.8 (19.1)	0.015*
Socialization	63.3 (18.84)	46.5 (20.4)	0.02*
Motor	76.0 (7.04)	50.1 (20.5)	< 0.001**

ISSN: 1866-1955