Fig. 1

Results of voxel-based morphometry (VBM). Statistical parametric maps (SPM) are projected on coronal slices of the MNI152 template illustrating regions with reduced GM volume in women with a 47,XXX karyotype. (a) Extended clusters showing gray matter volume reduction comprising hippocampus, amygdala, putamen, insula. (b) Extended clusters in the cerebellum. Results were FWE-corrected with a voxel threshold of T > 6.14; p < .05